Which therapy is an example of adoptive immunity in cancer treatment?

Which therapy is an example of adoptive immunity in cancer treatment?

• A. Infusion of tumor-infiltrating lymphocytes
• B. Vaccination with tumor antigens
• C. Monoclonal antibody therapy
• D. Antibiotic therapy

Answer: (A)

Adoptive cell transfer is about giving the patient immune cells that have been prepared outside the body to enhance the anti-tumor response. Infusion of tumor-infiltrating lymphocytes fits this perfectly: T cells are taken from the patient's tumor, expanded and activated in the lab, and then infused back to attack the cancer. This is a direct transfer of immune cells designed to fight the tumor. Vaccination with tumor antigens aims to stimulate the patient’s own immune system in vivo without transferring cells. Monoclonal antibody therapy provides antibodies to target the tumor but does not involve transferring active immune cells. Antibiotic therapy treats infections, not cancer immunotherapy.

Adoptive cell transfer is about giving the patient immune cells that have been prepared outside the body to enhance the anti-tumor response. Infusion of tumor-infiltrating lymphocytes fits this perfectly: T cells are taken from the patient's tumor, expanded and activated in the lab, and then infused back to attack the cancer. This is a direct transfer of immune cells designed to fight the tumor.

Vaccination with tumor antigens aims to stimulate the patient’s own immune system in vivo without transferring cells. Monoclonal antibody therapy provides antibodies to target the tumor but does not involve transferring active immune cells. Antibiotic therapy treats infections, not cancer immunotherapy.