Which therapy exemplifies adoptive immunity by infusing patient-derived immune cells after expansion?

Which therapy exemplifies adoptive immunity by infusing patient-derived immune cells after expansion?

• A. Passive immunity
• B. Natural immunity
• C. Adoptive immunity
• D. Active immunity

Answer: (C)

Adoptive immunity is about taking immune cells from the patient, expanding or engineering them outside the body, and then infusing them back to boost the immune response. This directly describes therapies like CAR-T cells or tumor-infiltrating lymphocytes, where a patient’s own cells are expanded (and often modified) in the lab before being reinfused to fight cancer. Passive immunity would involve transferring antibodies or other immune components, not expanding and returning patient-derived cells. Active immunity involves the body generating its own response, typically through vaccination or infection, rather than reinfusing lab-expanded cells. Natural immunity refers to the body’s inherent defenses, not a therapeutic infusion.

Adoptive immunity is about taking immune cells from the patient, expanding or engineering them outside the body, and then infusing them back to boost the immune response. This directly describes therapies like CAR-T cells or tumor-infiltrating lymphocytes, where a patient’s own cells are expanded (and often modified) in the lab before being reinfused to fight cancer.

Passive immunity would involve transferring antibodies or other immune components, not expanding and returning patient-derived cells. Active immunity involves the body generating its own response, typically through vaccination or infection, rather than reinfusing lab-expanded cells. Natural immunity refers to the body’s inherent defenses, not a therapeutic infusion.