What term describes a transplantation of tissue between genetically different individuals of the same species?

What term describes a transplantation of tissue between genetically different individuals of the same species?

• A. Allograft
• B. Isograft
• C. Autograft
• D. Xenograft

Answer: (A)

In transplantation immunology, the term describes tissue transferred between genetically different individuals of the same species. That scenario is called an allograft. It’s the common situation in human organ transplants, where donor and recipient are not genetically identical, so immune differences (like HLA/MHC antigens) can trigger rejection unless immunosuppression is used. For contrast, autograft refers to tissue moved within the same individual, so there’s no foreign immune challenge. Isograft describes tissue transferred between genetically identical individuals, such as identical twins, where rejection is minimal. Xenograft involves transplanting tissue across species, which typically faces strong rejection due to major species differences.

In transplantation immunology, the term describes tissue transferred between genetically different individuals of the same species. That scenario is called an allograft. It’s the common situation in human organ transplants, where donor and recipient are not genetically identical, so immune differences (like HLA/MHC antigens) can trigger rejection unless immunosuppression is used.

For contrast, autograft refers to tissue moved within the same individual, so there’s no foreign immune challenge. Isograft describes tissue transferred between genetically identical individuals, such as identical twins, where rejection is minimal. Xenograft involves transplanting tissue across species, which typically faces strong rejection due to major species differences.