What term describes a transplant between genetically identical individuals?

What term describes a transplant between genetically identical individuals?

• A. Autograft
• B. Allograft
• C. Xenograft
• D. Isograft

Answer: (D)

Transplants between genetically identical individuals are called isografts (synonymous with syngeneic grafts). This fits because donor and recipient share an identical set of histocompatibility antigens, so the immune system largely sees the tissue as self and mounts little to no rejection. Identical twins are the classic example. Autografts are tissues moved within the same person, which also have low rejection risk but involve only one individual. Allografts are between non-identical individuals of the same species, carrying risks from HLA differences. Xenografts are between different species, with a much higher likelihood of rejection.

Transplants between genetically identical individuals are called isografts (synonymous with syngeneic grafts). This fits because donor and recipient share an identical set of histocompatibility antigens, so the immune system largely sees the tissue as self and mounts little to no rejection. Identical twins are the classic example.

Autografts are tissues moved within the same person, which also have low rejection risk but involve only one individual. Allografts are between non-identical individuals of the same species, carrying risks from HLA differences. Xenografts are between different species, with a much higher likelihood of rejection.