What is the major function of T regulatory cells?

What is the major function of T regulatory cells?

• A. Suppression of the immune response by producing TNF
• B. Suppression of the immune response by inducing IL-10
• C. Proliferation of the immune response by producing IL-2
• D. Proliferation of the immune response by inducing IL-4

Answer: (B)

Regulatory T cells act to keep the immune system in check by suppressing responses and maintaining tolerance. A key way they do this is by releasing anti-inflammatory signals, especially IL-10, which dampens the activity of effector T cells and other immune cells like macrophages. This suppressive function helps prevent autoimmunity and limit excessive inflammation. The other options describe promoting or proliferating immune responses: TNF drives inflammation, while IL-2 and IL-4 promote T cell proliferation and differentiation.

Regulatory T cells act to keep the immune system in check by suppressing responses and maintaining tolerance. A key way they do this is by releasing anti-inflammatory signals, especially IL-10, which dampens the activity of effector T cells and other immune cells like macrophages. This suppressive function helps prevent autoimmunity and limit excessive inflammation. The other options describe promoting or proliferating immune responses: TNF drives inflammation, while IL-2 and IL-4 promote T cell proliferation and differentiation.